Zymeworks Inc. (ZYME) Stock

HealthcareBiotechnology Website

ZYME has an Alpha Score of 56 out of 100 (moderate), computed on Aug 23, 2026 from 3 of 4 sub-scores. 3 of the hedge funds AlphaScala tracks reported ZYME in 13F filings for the quarter ended Jun 30, 2026; the largest reported position is Citadel's at $23.90M. Company insiders reported 0 open-market buys and 1 sale on SEC Form 4 in the 90 days to Oct 21, 2026.

What is ZYME's Alpha Score?

How it works →

Alpha Score of 55 reflects moderate overall profile with strong momentum, weak value, weak quality. Based on 3 of 4 signals – score is capped at 90 until remaining data ingests.

Momentum
100
Strong
Value
43
Weak
Quality
34
Poor

Computed from 3 of 4 sub-scores; a sub-score is left out when its inputs are missing, and the composite is capped accordingly.

Computed Aug 23, 2026 · 60 days ago; due for a rescore

A rules-based research rating, not a recommendation to buy or sell.

Which hedge funds own ZYME?

From 13F filings
FundShares HeldPosition ValueChange vs prior Q
Citadel
Ken Griffin
914K$23.90M-21%
D.E. Shaw
David Shaw
145K$3.79M-39%
Marshall Wace41K$1.07M+27%

13F holdings as of Jun 30, 2026

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Are Zymeworks Inc. insiders buying or selling?

SEC Form 4 filings
90 days to Oct 21, 2026
Buys
0
Sells
1
Net $
-$358K
Unique insiders
1
DateInsiderRoleTypeSharesValue
Oct 9, 26Schayowitz AdamEVP, Head of R&DSELL13.8K$358K

SEC Form 4 filings as of Oct 21, 2026

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What are ZYME's key statistics?

EPS (TTM)
-2.01
Beta
1.32
Net Margin
-404.00%
ROE
-72.07%
Debt / Equity
0.00
52W High
$31.34
52W Low
$16.00

Key statistics as of Oct 21, 2026

How does ZYME's valuation compare with the Healthcare sector?

MetricZYMEHealthcare medianCompanies in median
Net margin-404.00%9.40%92
Return on equity-72.07%11.24%99

Medians over the Healthcare stocks whose key statistics were refreshed in the last 35 days (newest Oct 22, 2026). P/E excludes loss-making companies.

ZYME price chart

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What does Zymeworks Inc. do?

Zymeworks Inc. is a biotechnology company that focuses on innovating biotherapeutics for the treatment of cancer and autoimmune diseases. The company's core mission revolves around developing novel, multifunctional therapeutics with the potential to improve efficacy and reduce side effects compared to conventional cancer treatments. Zymeworks utilizes its proprietary platforms, such as the Azymetric and EFECT technologies, which enable the creation of multifunctional antibody therapeutics. These assets are significant in sectors such as oncology and immunology, addressing unmet needs with therapies aimed at complex and difficult-to-treat conditions. Based in Canada, Zymeworks collaborates with leading global pharmaceutical companies to enhance the reach and impact of its research. In the financial market, Zymeworks Inc. is notable for its strategic partnerships and potential for contributing to advancements in precision medicine, emphasizing its role not only in scientific innovation but also as a key player in the biotech industry's approach to personalized healthcare solutions.

CEO
Mr. Kenneth H. Galbraith C.A.
Employees
264
Market Cap
$2.09B
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