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All Stocks/Healthcare/VRTX

Vertex Pharmaceuticals Incorporated

VRTXNASDAQ
HealthcareDrug Manufacturers - Specialty Website
Alpha Score
49
Weak
Signal SnapshotMarket signals →
Alpha Score
49 · Weak
Alpha Score of 49 reflects weak overall profile with weak momentum, poor value, strong quality, moderat...
Updated May 5
Insider Activity
-$26.6M net
0 buys and 21 sells in the 90-day rollup.
Form 4 · Apr 1
13F Holder
Citadel
$358.14M reported position; latest action: new.
Ken Griffin
Latest Filing
No filing digest
Recent 10-K, 10-Q, and 8-K summaries will appear here when available.
SEC digest
Price ChartPowered by TradingView
Ask about VRTXAI research agent
Alpha Score BreakdownHow it works →

Alpha Score of 49 reflects weak overall profile with weak momentum, poor value, strong quality, moderate sentiment.

Momentum
48
Weak
Value
17
Poor
Quality
80
Strong
Sentiment
50
Weak
Key StatisticsUpdated Apr 15
P/E Ratio
46.72
Forward P/E
—
PEG Ratio
—
EPS (TTM)
9.51
Dividend Yield
—
Beta
0.35
Revenue (TTM)
—
Net Margin
32.94%
ROE
22.70%
Debt / Equity
0.01
52W High
$509.50
52W Low
$366.54
Daily CommentaryAI-written, data-grounded

Vertex Pharmaceuticals Maintains Strong Quality Metrics Amidst Valuation Headwinds

Apr 15, 2026

Vertex Pharmaceuticals (VRTX) continues to trade in the upper quartile of its 52-week range of $366.54 to $509.50, reflecting sustained investor interest despite a high valuation profile. The company currently commands a P/E ratio of 46.72, which contrasts with its moderate revenue growth rate of 8.9% year-over-year. While the stock faces pressure from its value sub-score of 16.6, the underlying financial health remains robust. Vertex reports an EPS of 9.51 and a net margin of 32.9%, contributing to a strong quality sub-score of 80.2. This quality metric highlights the company’s operational efficiency and ability to maintain profitability within the healthcare sector. Current momentum sits at 48.3, suggesting a period of consolidation as market participants weigh the premium valuation against the firm’s consistent margin performance. The absence of a sentiment score leaves the stock driven primarily by its fundamental quality and price positioning relative to its annual highs. Investors should monitor upcoming quarterly earnings reports to see if revenue growth accelerates to justify the current earnings multiple.

Insider ActivitySEC Form 4 filings
Buys (90d)
0
Sells (90d)
21
Net $ (90d)
$-26.6M
Unique insiders
5
DateInsiderRoleTypeSharesValue
Apr 1, 26Liu JoyEVP and Chief Legal OfficerSELL978$439K
Mar 27, 26Bozic CarmenEVP and CMOSELL2.3K$1.1M
Mar 13, 26Bozic CarmenEVP and CMOSELL2.3K$1.1M
Mar 11, 26Mckechnie DuncanEVP, Chief Commercial OfficerSELL2.6K$1.3M
Mar 4, 26Mckechnie DuncanEVP, Chief Commercial OfficerSELL2.4K$1.2M
Mar 2, 26Liu JoyEVP and Chief Legal OfficerSELL892$442K
Feb 27, 26Kewalramani ReshmaCEO & PresidentSELL400$192K
Feb 27, 26Kewalramani ReshmaCEO & PresidentSELL120$58K
Feb 27, 26Kewalramani ReshmaCEO & PresidentSELL240$116K
Feb 27, 26Kewalramani ReshmaCEO & PresidentSELL2.5K$1.2M
See cluster-buy signals across all tickers →
Top Institutional HoldersFrom 13F filings
FundShares HeldPosition ValueAction (latest Q)
Citadel
Ken Griffin
790K$358.14MNEW
Renaissance Technologies
Jim Simons (founder)
505K$228.97MNEW
Marshall Wace206K$93.23MNEW
D.E. Shaw
David Shaw
43K$19.27MNEW
Point72
Steve Cohen
28K$12.74MNEW
ARK Invest
Cathie Wood
26K$11.83MNEW
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About Vertex Pharmaceuticals Incorporated

Vertex Pharmaceuticals Incorporated is a leading biotechnology company founded in 1989 and headquartered in Boston, Massachusetts. It specializes in the discovery, development, and commercialization of transformative therapies, with a primary focus on cystic fibrosis (CF), a life-threatening genetic disease. The company markets a portfolio of CF treatments, including TRIKAFTA/KAFTRIO for patients aged 2 and older with at least one F508del mutation, ALYFTREK for those 6 years and older, SYMDEKO/SYMKEVI and ORKAMBI for patients 6 years and 1 year or older respectively, and KALYDECO for infants as young as 1 month with specific CF mutations. Vertex Pharmaceuticals Incorporated plays a pivotal role in the pharmaceuticals and biotech sector by addressing unmet needs in rare diseases through innovative small-molecule drugs. Its pipeline extends beyond CF into areas like acute and neuropathic pain, with candidates such as VX-548 advancing toward regulatory approval. With trailing twelve-month revenue of approximately $9.72 billion and a market capitalization around $86-101 billion, the company demonstrates significant financial strength and global market presence across multiple exchanges.

CEO
Dr. Reshma Kewalramani FASN, M.D.
Employees
6,400
Quick Facts
ExchangeNASDAQ
SectorHealthcare
IndustryDrug Manufacturers - Specialty
Market Cap—
Avg Volume1.18M
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Key Dates

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