
Billionaire Mark Cuban says doctors should help patients configure ChatGPT, Claude for treatment. He argues AI can't replace real-time judgment but will eliminate 'bullshit administrivia.'
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Mark Cuban spent Wednesday on X arguing that doctors should teach patients how to use AI tools like ChatGPT and Claude, not fear being replaced by them.
In a series of posts, the billionaire entrepreneur pushed back against predictions that AI will eliminate medical jobs. "No chance radiologists get replaced," Cuban wrote. He said a model is outdated the minute it is released and that model usage costs more than a radiologist.
Cuban argued that AI cannot replicate what a doctor does in real time – observing a patient who suddenly vomits, seeing someone collapse and starting CPR, discussing a case with another physician who knows the patient.
He later refined his position. AI will replace most tasks doctors perform, Cuban wrote. The reason is not that machines can practice medicine independently. Clinicians spend too much time on what he called "bullshit administrivia" created by healthcare conglomerates. His proposed fix: "Replace the middlemen with AI."
Cuban also proposed a new role for physicians. He said private-practice doctors could sit down with patients and configure tools such as Claude, ChatGPT, Gemini, and Grok with personalized instructions, skills, and prompts. The LLM would then share results with the doctor, allowing physicians to interact with both the patient and the patient's AI.
"If I was a doctor with a private practice, I would offer to sit with the patient and configure their Claude, ChatGPT, Gemini and Grok with instructions and skills," Cuban wrote.
Cuban's focus on healthcare intermediaries is not new. In 2022 he cofounded Mark Cuban Cost Plus Drug Company, an online pharmacy built around transparent pricing that bypasses traditional pharmacy benefit managers. Disrupting the opaque drug-pricing system has become one of his signature business projects.
His latest posts build on warnings he made last month. Cuban said AI could create an arms race between providers and insurers, with doctors using agents to improve care while conglomerates deploy their own to "delay and deny." He has also urged employers to run healthcare contracts through chatbots to identify hidden costs and unfavorable terms.
Cuban's comments came as AI's role in medicine moves beyond chatbots. On Wednesday, Moderna and Merck said their experimental personalized mRNA cancer vaccine, intismeran, had met key endpoints in a Phase 3 melanoma trial. The treatment uses genetic sequencing and algorithms to help select tumor mutations for a vaccine tailored to each patient – an example of AI supporting medical treatment rather than replacing the clinician.
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