
Outer Biosciences uses live human skin from plastic surgery to test cosmetics ingredients, backed by $23M from top VCs. Lady Gaga sits on the board. Her fiancé Michael Polansky co-founded the startup.
Michael Polansky, the 42-year-old Harvard graduate engaged to Lady Gaga, has launched a biotechnology startup that uses live human skin from plastic surgery to test cosmetic and pharmaceutical ingredients. Outer Biosciences raised $23 million from leading Silicon Valley venture firms, according to the company. Lady Gaga sits on its board of directors.
The company takes "full-thickness" skin tissue discarded during surgeries and keeps it alive for up to a month, Polansky told TechCrunch. That allows researchers to study how specific molecules and chemical mechanisms affect skin health – something not possible with animal models or synthetic skin substitutes, the company's website says. Pharmaceutical and beauty brands use the data to identify which ingredients actually work on living human tissue.
Outer Biosciences was co-founded in 2022 by Polansky, Kyung-Jin Jang, Chris Hinojosa and Stanley King. The $23 million round was backed by several top Silicon Valley firms; the company did not name them in the interview. Polansky said the technology fills a gap in the testing market, where most models cannot replicate the complexity of live human skin.
Polansky praised Gaga's business instincts in the interview. "People really haven't gotten to know a certain side of her publicly … She's such a brilliant businessperson," he said. Gaga launched her own makeup line, Haus Labs, in 2019, and the brand is reportedly thriving. Polansky helped manage her world tour that began in July 2025, which he described as a "200-person startup that travels around the world every day."
The couple got engaged on a hiking trip in April 2024. Gaga told Jimmy Kimmel that Polansky asked her for permission to propose before dropping to one knee. "He wanted to know if it was OK to propose before he proposed. I was like, 'Yes! It's so OK!'", she said. On Bruno Mars' iHeartRadio livestream in March, Gaga said the wedding will happen "soon."
Outer Biosciences plans to use the new capital to expand its tissue-processing capacity and sign partnerships with additional pharmaceutical and beauty companies, the company said.
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