
Kalshi and AppliedXL launched a pilot letting users trade on clinical trial endpoints and FDA decisions, with extra insider-trading safeguards.
Prediction market Kalshi and public intelligence firm AppliedXL launched a pilot program Thursday that lets users trade on clinical trial outcomes and FDA regulatory decisions.
The companies said in a press release that contracts available at launch include “Will AR1001’s POLARIS-AD Phase 3 trial meet its primary endpoint in early Alzheimer’s disease?” and “Will the FDA approve Gilead/Arcellx’s anito-cel for relapsed/refractory multiple myeloma?”
The markets make drug-development odds public, continuously updated and based on evidence beyond what the trial sponsor supplies, according to the release. They also let investors act on their view about a single drug rather than the whole business at once, as public equities require.
Kalshi added extra measures to prevent insider trading on top of its existing rules, the release said.
“Drug development is one of the most important and most information-constrained industries on earth,” Kalshi CEO Tarek Mansour said in the release. “The data that determines which drugs advance and which don’t is largely locked away from the people who need it most. Surfacing information is what Kalshi is for, and we are committed to doing it right: compliance-first, carefully scoped and built for the long-term.”
AppliedXL, which tracks pharmaceutical data, will provide the resolution infrastructure for the new markets, per the release.
“Clinical trial results are rarely handed to you cleanly,” AppliedXL Co-Founder and CEO Francesco Marconi said in the release. “They come out in pieces, scattered across registries, regulatory filings and company statements, and the press releases often put a favorable spin on what the data actually shows. Resolving a market means reconciling all of that back to the primary source, which is what we built AppliedXL to do.”
Wall Street broker Bernstein expects prediction market volume to rise from $51 billion last year to $240 billion this year and $1 trillion by 2030, it was reported in April.
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