Chemistry Ventures: $350M Debut Fund, No Second Fund Yet

Chemistry Ventures was founded in October 2024 by Mark Goldberg, formerly of Index Ventures, Ethan Kurzweil from Bessemer Venture Partners, and Kristina Shen, who came over from Andreessen Horowitz. The firm closed a $350 million debut fund aimed at software startups in 2024, reportedly faster than expected due to oversubscription from limited partners.

The firm targets seed and Series A investments, with a stated focus on fintech and infrastructure software. In April 2026, Chemistry participated in a $30 million funding round for ComfyUI, an AI startup valued at $500 million in that deal.

No announcements or filings for a $500 million second fund have been confirmed as of July 2026. Chemistry Ventures has also shown no involvement in cryptocurrency, blockchain protocols, or digital asset investments, positioning it as a conventional software-focused venture capital firm.