
Air Force, Navy, and Coast Guard veterans developed ALS at rates 15-29% higher than Army veterans, a new study of nearly 10 million VA patients found. Officers faced 64% higher risk.
Veterans who served in the Air Force, Navy, or Coast Guard developed ALS at rates 15% to 29% higher than Army veterans, a study published last month in the journal Neurology found.
The analysis covered nearly 10 million veterans who received Department of Veterans Affairs healthcare between 2000 and 2024. Of those, almost 14,500 had an ALS diagnosis. Officers faced a 64% higher risk than enlisted personnel.
Researchers did not identify the specific jobs or exposures driving the gap. ALS, or amyotrophic lateral sclerosis, is a degenerative disease that destroys nerve cells controlling voluntary movement. Patients progressively lose the ability to speak, eat, move, and breathe. The disease is often hard to diagnose and is fatal.
"Military service is a known risk factor for the development of ALS," Marc Weisskopf, an environmental epidemiologist at Harvard and a study author, said in a university announcement. "Little is known about what factors may contribute to that risk."
Weisskopf cautioned that ALS remains rare, so even statistically significant differences by branch and rank represent only modest increases in absolute risk.
Previous studies have also linked military service to higher ALS rates, according to the National Institute of Neurological Disorders and Stroke. Veterans may face exposure to lead, pesticides, and other toxins. ALS is more common in older white men, though it affects all populations.
The branch and rank differences are unexplained. Weisskopf said in an American Academy of Neurology press release that officers and enlisted personnel may face different work conditions.
"Officers tend to experience more psychosocial stress, with pilots experiencing high G-forces, noise and vibration as well as circadian disruption," he said. "Enlisted personnel usually experience more extreme physical exercise, heavy weapons use and handling of fuels and solvents."
Roughly 46% of veterans with an ALS diagnosis served in the Army, in line with the Army's share of the veteran population studied.
After adjusting for age, sex, race, and ethnicity, male Air Force veterans had a 29% higher ALS rate than male Army veterans. Male Coast Guard veterans had a 26% higher rate. Male Navy veterans had a 15% higher rate. Male Marine veterans had a 22% lower rate than Army veterans.
Differences were larger among men under 61 than among those over 75.
The researchers said they had limited ability to assess differences among women because ALS is rare and women make up 18% of the military population. Among the women included, female officers faced a 72% higher risk than enlisted women.
"Our findings suggest that officers and those serving in the Air Force, Navy, or Coast Guard may have been exposed to military environments that increase risk for ALS," Weisskopf said. "Future research should aim to identify these exposures."
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