A16z Leads $30M Series A for AI Automating Healthcare Phone Calls

Andreessen Horowitz led a $30 million Series A for Prosper AI on June 22. The healthtech startup builds voice agents designed to handle the phone-heavy administrative tasks that burn through an estimated $450 billion a year in US healthcare. Prior authorizations and insurance verification dominate those costs.

The round brought in Base10 as a new investor, with Emergence Capital, Y Combinator, and Company Ventures joining again. Prosper AI now has total funding between $35 million and $36.6 million, counting a $5 million seed that closed in September 2025.

Revenue has grown roughly fivefold since that seed, the company said. Prosper AI now manages workflows for more than 150,000 physicians and handles thousands of patient interactions daily. It claims an 80% win rate in competitive evaluations.

The platform slots into existing electronic health record and revenue-cycle management systems. That lets its voice agents pull patient data, verify insurance details, and complete administrative tasks without requiring practices to replace their existing tech.

Founders Xavier de Gracia and Josep Mingot bring backgrounds in medical practices, call center operations, and product development. Prosper AI plans to spend the new capital on expanding its engineering and customer-facing teams alongside deepening integrations with EHR and RCM platforms.