Pantera Capital Leads $4.3M Seed Round for Orthogonal

Orthogonal, a startup building infrastructure for autonomous agents, raised $4.3 million in seed funding. Pantera Capital led the round. Y Combinator, Pioneer Fund, Decasonic, Blast, Outbound, Surreal, and other investors participated.

The company describes itself as a discovery and orchestration layer for the internet, with payment built into the platform. Through a single integration, agents can find new capabilities and access services, then pay for them, Orthogonal said.

Former leaders from Coinbase, Vercel, Google, and Amazon Robotics founded Orthogonal. The team is building the infrastructure that enables autonomous agents to transact and operate across the web.

The round closed in June 2026, according to the company. Orthogonal did not disclose the valuation or additional terms.